ONCO/Reveal™
Solid Tumor Genetic Test
What is Solid Tumor Genetic Test?
It detects numerous, relevant gene regions of interest for researchers looking to explore the genetic sequences of both germline and formalin-fixed paraffin-embedded (FFPE) DNA samples from solid tumor samples. The panel utilizes Pillar Biosciences’ proprietary SLIMamp® (stem-loop inhibition mediated amplification) technology, allowing researchers to amplify regions of interest in a simple, multiplex reaction for subsequent sequencing on a sequencer using a paired-end read length of 150 (2×150).

In 2020, Asia reported the most outrageous number of new cancer cases and death worldwide. According to global data conducted by World Health Organization, approximately 9 million of new cases were diagnosed respectively among Asian, together with 5 million deaths.
Reduction of mortality from a specific cancer can be achieved by early cancer screening and diagnosis. With the next generation sequencing (NGS) technique, it holds the promise of detecting tumour mutations on either tumour cells or free circulating tumour DNA in a comprehensive and concise way for physicians to select appropriate targeted therapeutical drugs for cancer treatment. An early diagnosis opens the door to future care and cancer treatment, increasing the overall survival rate.
Target
Researchers looking to explore the genetic sequences of both germline and formalin-fixed paraffin-embedded (FFPE) DNA from solid tumour samples.
Table 1: Gene List
AKT1 | DDR2 | FGFR2 | HRAS | NRAS | PTEN | SRSF2 |
ALK | EGFR | FGFR3 | IDH1 | NTRK1 | PTPN11 | STK11 |
ARAF | EIF1AX | GNA11 | IDH2 | PDGFRA | RAC1 | TERT |
BRAF | ERBB2 | GNAQ | KIT | PIK3CA | RAF1 | TP53 |
CDKN2A | ERBB4 | GNAS | KRAS | PLCB4 | RET | TSHR |
CTNNB1 | FBXW7 | H3F3A | MAP2K1 | POLD1 | SF3B1 | |
CYSLTR2 | FGFR1 | HIST1H3B | MET | POLE | SMAD4 |
Table 1: Gene List
AKT1 | DDR2 | FGFR2 | HRAS | NRAS |
PTEN | SRSF2 | ALK | EGFR | FGFR3 |
IDH1 | NTRK1 | PTPN11 | STK11 | ARAF |
PIK3CA | RAF1 | TP53 | CDKN2A | ERBB4 |
CTNNB1 | FBXW7 | H3F3A | MAP2K1 | POLD1 |
SF3B1 | CYSLTR2 | FGFR1 | HIST1H3B | MET |
POLE | SMAD4 |
AKT1
|
Solid Tumor Genetic Test
|
---|---|
Content
|
47 genes detected from solid tumour (please refer to table 1 for details)
|
Sequencing Platform
|
NGS
|
Sequencing Type
|
Amplicon based sequencing
|
Variants Type
|
SNVs, indel and medium indels
|
Sample Type
|
FFPE
|
TAT
|
7 working days**
|
Workflow

Pre-sales consultation

Sign the consent form, collect paraffin-embedded sections

Send the specimen to the laboratory

Analyse the experimental data

A total of 7 working days to complete the report**
**Only applicable to the sample that fulfil the QC requirements.